It was just days ago that we touched on the issue of COVID-19 vaccine negative effectiveness again (for deaths), and also a few days before that (for infections). The latter concerned a study by Shrestha et al., covering late 2022 to early 2023. Four of the six authors, again led by Shrestha, are back for another bite of the cherry, with another study (preprint) now covering early to mid 2023. Source.
The authors found: “The cumulative incidence of COVID-19 was lower in the “not up-to-date” than in the “up-to-date” state. On multivariable analysis, not being “up-to-date” with COVID-19 vaccination was associated with lower risk of COVID-19 (HR, 0.77; 95% C.I., 0.69-0.86; P-value, <0.001).” They conclude: “Since the XBB lineages became dominant, adults “not up-to-date” by the CDC definition have a lower risk of COVID-19 than those “up-to-date” on COVID-19 vaccination, bringing into question the value of this risk classification definition.”
Okay then.
Extra: If the COVID-19 vaccines increase one’s chance of COVID-19 infection, hospitalisation, and death, how can they be ‘safe and effective’? If they truly are negatively effective, we should no longer speak of weighing up benefits against harms, instead noting that the equation would now just be adding harms upon harms.